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Last Name
Institution

Igor Theurl, M.D.

TitleResearch Fellow in Medicine (EXT)
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
8th Flr, Program in Membrane Bio
185 Cambridge St
Boston MA 02114
Phone617/724-9078
Fax617/643-3182

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Lass-Flörl C, Mutschlechner W, Aigner M, Grif K, Marth C, Girschikofsky M, Grander W, Greil R, Russ G, Cerkl P, Eller M, Kropshofer G, Eschertzhuber S, Kathrein H, Schmid S, Beer R, Lorenz I, Theurl I, Nachbaur D. Utility of PCR in diagnosis of invasive fungal infections: real-life data from a multicenter study. J Clin Microbiol. 2013 Mar; 51(3):863-8.
    View in: PubMed
  2. Schroll A, Eller K, Feistritzer C, Nairz M, Sonnweber T, Moser PA, Rosenkranz AR, Theurl I, Weiss G. Lipocalin-2 ameliorates granulocyte functionality. Eur J Immunol. 2012 Dec; 42(12):3346-57.
    View in: PubMed
  3. Wermke M, Schmidt A, Middeke JM, Sockel K, von Bonin M, Schönefeldt C, Mair S, Plodeck V, Laniado M, Weiss G, Schetelig J, Ehninger G, Theurl I, Bornhäuser M, Platzbecker U. MRI-Based Liver Iron Content Predicts for Nonrelapse Mortality in MDS and AML Patients Undergoing Allogeneic Stem Cell Transplantation. Clin Cancer Res. 2012 Dec 1; 18(23):6460-8.
    View in: PubMed
  4. Sonnweber T, Ress C, Nairz M, Theurl I, Schroll A, Murphy AT, Wroblewski V, Witcher DR, Moser P, Ebenbichler CF, Kaser S, Weiss G. High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption. J Nutr Biochem. 2012 Dec; 23(12):1600-8.
    View in: PubMed
  5. Rauch PJ, Chudnovskiy A, Robbins CS, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK. Innate response activator B cells protect against microbial sepsis. Science. 2012 Feb 3; 335(6068):597-601.
    View in: PubMed
  6. Nairz M, Sonnweber T, Schroll A, Theurl I, Weiss G. The pleiotropic effects of erythropoietin in infection and inflammation. Microbes Infect. 2012 Mar; 14(3):238-46.
    View in: PubMed
  7. Mair SM, Nairz M, Bellmann-Weiler R, Muehlbacher T, Schroll A, Theurl I, Moser PL, Talasz H, Fang FC, Weiss G. Nifedipine affects the course of Salmonella enterica serovar Typhimurium infection by modulating macrophage iron homeostasis. J Infect Dis. 2011 Sep 1; 204(5):685-94.
    View in: PubMed
  8. Theurl I, Schroll A, Nairz M, Seifert M, Theurl M, Sonnweber T, Kulaksiz H, Weiss G. Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo. Haematologica. 2011 Dec; 96(12):1761-9.
    View in: PubMed
  9. Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G. Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats. Blood. 2011 Nov 3; 118(18):4977-84.
    View in: PubMed
  10. Tjalsma H, Laarakkers CM, van Swelm RP, Theurl M, Theurl I, Kemna EH, van der Burgt YE, Venselaar H, Dutilh BE, Russel FG, Weiss G, Masereeuw R, Fleming RE, Swinkels DW. Mass spectrometry analysis of hepcidin peptides in experimental mouse models. PLoS One. 2011; 6(3):e16762.
    View in: PubMed
  11. Nairz M, Schroll A, Moschen AR, Sonnweber T, Theurl M, Theurl I, Taub N, Jamnig C, Neurauter D, Huber LA, Tilg H, Moser PL, Weiss G. Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-?B-inducible immune pathways. Immunity. 2011 Jan 28; 34(1):61-74.
    View in: PubMed
  12. Pichler I, Minelli C, Sanna S, Tanaka T, Schwienbacher C, Naitza S, Porcu E, Pattaro C, Busonero F, Zanon A, Maschio A, Melville SA, Grazia Piras M, Longo DL, Guralnik J, Hernandez D, Bandinelli S, Aigner E, Murphy AT, Wroblewski V, Marroni F, Theurl I, Gnewuch C, Schadt E, Mitterer M, Schlessinger D, Ferrucci L, Witcher DR, Hicks AA, Weiss G, Uda M, Pramstaller PP. Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. Hum Mol Genet. 2011 Mar 15; 20(6):1232-40.
    View in: PubMed
  13. Sonnweber T, Theurl I, Seifert M, Schroll A, Eder S, Mayer G, Weiss G. Impact of iron treatment on immune effector function and cellular iron status of circulating monocytes in dialysis patients. Nephrol Dial Transplant. 2011 Mar; 26(3):977-87.
    View in: PubMed
  14. Volgger B, Kurz K, Zöschg K, Theurl I, Ciresa-König A, Marth C, Weiss G. Importance of erythropoetin receptor expression in tumour tissue for the clinical course of breast cancer. Anticancer Res. 2010 Sep; 30(9):3721-6.
    View in: PubMed
  15. Bellmann-Weiler R, Ausserwinkler M, Kurz K, Theurl I, Weiss G. Clinical potential of C-reactive protein and procalcitonin serum concentrations to guide differential diagnosis and clinical management of pneumococcal and Legionella pneumonia. J Clin Microbiol. 2010 May; 48(5):1915-7.
    View in: PubMed
  16. Schroll A, Eller K, Huber JM, Theurl IM, Wolf AM, Weiss G, Rosenkranz AR. Tim3 is upregulated and protective in nephrotoxic serum nephritis. Am J Pathol. 2010 Apr; 176(4):1716-24.
    View in: PubMed
  17. Theurl I, Finkenstedt A, Schroll A, Nairz M, Sonnweber T, Bellmann-Weiler R, Theurl M, Seifert M, Wroblewski VJ, Murphy AT, Witcher D, Zoller H, Weiss G. Growth differentiation factor 15 in anaemia of chronic disease, iron deficiency anaemia and mixed type anaemia. Br J Haematol. 2010 Feb; 148(3):449-55.
    View in: PubMed
  18. Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, Seifert M, Crouch ML, Hantke K, Akira S, Fang FC, Weiss G. Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood. 2009 Oct 22; 114(17):3642-51.
    View in: PubMed
  19. Theurl I, Aigner E, Theurl M, Nairz M, Seifert M, Schroll A, Sonnweber T, Eberwein L, Witcher DR, Murphy AT, Wroblewski VJ, Wurz E, Datz C, Weiss G. Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications. Blood. 2009 May 21; 113(21):5277-86.
    View in: PubMed
  20. Finkenstedt A, Bianchi P, Theurl I, Vogel W, Witcher DR, Wroblewski VJ, Murphy AT, Zanella A, Zoller H. Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency. Br J Haematol. 2009 Mar; 144(5):789-93.
    View in: PubMed
  21. Theurl M, Theurl I, Hochegger K, Obrist P, Subramaniam N, van Rooijen N, Schuemann K, Weiss G. Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression. J Mol Med (Berl). 2008 Jul; 86(7):825-35.
    View in: PubMed
  22. Aigner E, Theurl I, Theurl M, Lederer D, Haufe H, Dietze O, Strasser M, Datz C, Weiss G. Pathways underlying iron accumulation in human nonalcoholic fatty liver disease. Am J Clin Nutr. 2008 May; 87(5):1374-83.
    View in: PubMed
  23. Aigner E, Theurl I, Haufe H, Seifert M, Hohla F, Scharinger L, Stickel F, Mourlane F, Weiss G, Datz C. Copper availability contributes to iron perturbations in human nonalcoholic fatty liver disease. Gastroenterology. 2008 Aug; 135(2):680-8.
    View in: PubMed
  24. Theurl I, Theurl M, Seifert M, Mair S, Nairz M, Rumpold H, Zoller H, Bellmann-Weiler R, Niederegger H, Talasz H, Weiss G. Autocrine formation of hepcidin induces iron retention in human monocytes. Blood. 2008 Feb 15; 111(4):2392-9.
    View in: PubMed
  25. Fritsche G, Nairz M, Theurl I, Mair S, Bellmann-Weiler R, Barton HC, Weiss G. Modulation of macrophage iron transport by Nramp1 (Slc11a1). Immunobiology. 2007; 212(9-10):751-7.
    View in: PubMed
  26. Nairz M, Theurl I, Ludwiczek S, Theurl M, Mair SM, Fritsche G, Weiss G. The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium. Cell Microbiol. 2007 Sep; 9(9):2126-40.
    View in: PubMed
  27. Ludwiczek S, Theurl I, Muckenthaler MU, Jakab M, Mair SM, Theurl M, Kiss J, Paulmichl M, Hentze MW, Ritter M, Weiss G. Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1. Nat Med. 2007 Apr; 13(4):448-54.
    View in: PubMed
  28. Metzler B, Jehle J, Theurl I, Ludwiczek S, Obrist P, Pachinger O, Weiss G. Short term protective effects of iron in a murine model of ischemia/reperfusion. Biometals. 2007 Apr; 20(2):205-15.
    View in: PubMed
  29. Eller P, Theurl I, Koppelstaetter F, Weiss G. Pyopneumothorax due to Streptococcus milleri. Wien Klin Wochenschr. 2006 May; 118(7-8):207.
    View in: PubMed
  30. Theurl I, Mattle V, Seifert M, Mariani M, Marth C, Weiss G. Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic disease. Blood. 2006 May 15; 107(10):4142-8.
    View in: PubMed
  31. Theurl I, Ludwiczek S, Eller P, Seifert M, Artner E, Brunner P, Weiss G. Pathways for the regulation of body iron homeostasis in response to experimental iron overload. J Hepatol. 2005 Oct; 43(4):711-9.
    View in: PubMed
  32. Theurl I, Fritsche G, Ludwiczek S, Garimorth K, Bellmann-Weiler R, Weiss G. The macrophage: a cellular factory at the interphase between iron and immunity for the control of infections. Biometals. 2005 Aug; 18(4):359-67.
    View in: PubMed
  33. Ludwiczek S, Theurl I, Bahram S, Schümann K, Weiss G. Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis. J Cell Physiol. 2005 Aug; 204(2):489-99.
    View in: PubMed
  34. Zoller H, McFarlane I, Theurl I, Stadlmann S, Nemeth E, Oxley D, Ganz T, Halsall DJ, Cox TM, Vogel W. Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease. Hepatology. 2005 Aug; 42(2):466-72.
    View in: PubMed
  35. Geier A, Gartung C, Theurl I, Weiss G, Lammert F, Dietrich CG, Weiskirchen R, Zoller H, Hermanns B, Matern S. Occult celiac disease prevents penetrance of hemochromatosis. World J Gastroenterol. 2005 Jun 7; 11(21):3323-6.
    View in: PubMed
  36. Theurl I, Zoller H, Obrist P, Datz C, Bachmann F, Elliott RM, Weiss G. Iron regulates hepatitis C virus translation via stimulation of expression of translation initiation factor 3. J Infect Dis. 2004 Aug 15; 190(4):819-25.
    View in: PubMed
  37. Ludwiczek S, Theurl I, Artner-Dworzak E, Chorney M, Weiss G. Duodenal HFE expression and hepcidin levels determine body iron homeostasis: modulation by genetic diversity and dietary iron availability. J Mol Med (Berl). 2004 Jun; 82(6):373-82.
    View in: PubMed
  38. Zoller H, Theurl I, Koch RO, McKie AT, Vogel W, Weiss G. Duodenal cytochrome b and hephaestin expression in patients with iron deficiency and hemochromatosis. Gastroenterology. 2003 Sep; 125(3):746-54.
    View in: PubMed
  39. Fritsche G, Dlaska M, Barton H, Theurl I, Garimorth K, Weiss G. Nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of IFN regulatory factor 1 expression. J Immunol. 2003 Aug 15; 171(4):1994-8.
    View in: PubMed
  40. Ludwiczek S, Aigner E, Theurl I, Weiss G. Cytokine-mediated regulation of iron transport in human monocytic cells. Blood. 2003 May 15; 101(10):4148-54.
    View in: PubMed
  41. Zoller H, Theurl I, Koch R, Kaser A, Weiss G. Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1. Blood Cells Mol Dis. 2002 Nov-Dec; 29(3):488-97.
    View in: PubMed
  42. Spizzo G, Obrist P, Ensinger C, Theurl I, Dünser M, Ramoni A, Gunsilius E, Eibl G, Mikuz G, Gastl G. Prognostic significance of Ep-CAM AND Her-2/neu overexpression in invasive breast cancer. Int J Cancer. 2002 Apr 20; 98(6):883-8.
    View in: PubMed
  43. Gander R, Eller P, Kaser S, Theurl I, Walter D, Sauper T, Ritsch A, Patsch JR, Föger B. Molecular characterization of rabbit phospholipid transfer protein: choroid plexus and ependyma synthesize high levels of phospholipid transfer protein. J Lipid Res. 2002 Apr; 43(4):636-45.
    View in: PubMed
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