Relaxin
"Relaxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A water-soluble polypeptide (molecular weight approximately 8,000) extractable from the corpus luteum of pregnancy. It produces relaxation of the pubic symphysis and dilation of the uterine cervix in certain animal species. Its role in the human pregnant female is uncertain. (Dorland, 28th ed)
| Descriptor ID |
D012065
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| MeSH Number(s) |
D06.472.334.734.769 D06.472.699.715 D12.644.548.762
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Relaxin".
Below are MeSH descriptors whose meaning is more specific than "Relaxin".
This graph shows the total number of publications written about "Relaxin" by people in Harvard Catalyst Profiles by year, and whether "Relaxin" was a major or minor topic of these publication.
Below are the most recent publications written about "Relaxin" by people in Profiles.
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Wang A, Karumanchi SA. Relaxin' with endothelial progenitor cells. Blood. 2012 Jan 12; 119(2):326-7.
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Segal MS, Sautina L, Li S, Diao Y, Agoulnik AI, Kielczewski J, McGuane JT, Grant MB, Conrad KP. Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice. Blood. 2012 Jan 12; 119(2):629-36.
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McGuane JT, Debrah JE, Sautina L, Jarajapu YP, Novak J, Rubin JP, Grant MB, Segal M, Conrad KP. Relaxin induces rapid dilation of rodent small renal and human subcutaneous arteries via PI3 kinase and nitric oxide. Endocrinology. 2011 Jul; 152(7):2786-96.
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McGowan BM, Stanley SA, Ghatei MA, Bloom SR. Relaxin-3 and its role in neuroendocrine function. Ann N Y Acad Sci. 2009 Apr; 1160:250-5.
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Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y. In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts. Nat Methods. 2009 Feb; 6(2):143-5.
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Davison JM, Homuth V, Jeyabalan A, Conrad KP, Karumanchi SA, Quaggin S, Dechend R, Luft FC. New aspects in the pathophysiology of preeclampsia. J Am Soc Nephrol. 2004 Sep; 15(9):2440-8.
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McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Sukhatme VP. Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. Am J Physiol Renal Physiol. 2003 Jul; 285(1):F59-67.
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Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK. Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation. Nat Med. 2003 Jun; 9(6):796-800.
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Loeken MR, Channing CP, D'Eletto R, Weiss G. Stimulatory effect of luteinizing hormone upon relaxin secretion by cultured porcine preovulatory granulosa cells. Endocrinology. 1983 Feb; 112(2):769-71.
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BRAVERMAN LE, INGBAR SH. Effects of preparations containing relaxin on thyroid function in the female rat. Endocrinology. 1963 Feb; 72:337-40.
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