Oximes
"Oximes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
| Descriptor ID |
D010091
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| MeSH Number(s) |
D02.092.570.665
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| Concept/Terms |
Oximes- Oximes
- Hydroxyimino Compounds
- Compounds, Hydroxyimino
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Below are MeSH descriptors whose meaning is more general than "Oximes".
Below are MeSH descriptors whose meaning is more specific than "Oximes".
This graph shows the total number of publications written about "Oximes" by people in Harvard Catalyst Profiles by year, and whether "Oximes" was a major or minor topic of these publication.
Below are the most recent publications written about "Oximes" by people in Profiles.
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Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, Hamid O, Schuchter L, Cebon J, Ibrahim N, Kudchadkar R, Burris HA, Falchook G, Algazi A, Lewis K, Long GV, Puzanov I, Lebowitz P, Singh A, Little S, Sun P, Allred A, Ouellet D, Kim KB, Patel K, Weber J. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med. 2012 Nov; 367(18):1694-703.
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Lee BF, Wang LW, Lin SH, Jhuo TJ, Chiu NT, Huang CC, Hsia CC, Shen LH. Tc-99m-HL91 imaging in the early detection of neuronal injury in a neonatal rat model of hypoxic ischemia. Crit Care Med. 2012 Jun; 40(6):1930-8.
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Kieltyka RE, Bastings MM, van Almen GC, Besenius P, Kemps EW, Dankers PY. Modular synthesis of supramolecular ureidopyrimidinone-peptide conjugates using an oxime ligation strategy. Chem Commun (Camb). 2012 Feb 1; 48(10):1452-4.
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O'Donoghue ML, Braunwald E, White HD, Serruys P, Steg PG, Hochman J, Maggioni AP, Bode C, Weaver D, Johnson JL, Cicconetti G, Lukas MA, Tarka E, Cannon CP. Study design and rationale for the Stabilization of pLaques usIng Darapladib-Thrombolysis in Myocardial Infarction (SOLID-TIMI 52) trial in patients after an acute coronary syndrome. Am Heart J. 2011 Oct; 162(4):613-619.e1.
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Boulant S, Kural C, Zeeh JC, Ubelmann F, Kirchhausen T. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol. 2011 Sep; 13(9):1124-31.
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White H, Held C, Stewart R, Watson D, Harrington R, Budaj A, Steg PG, Cannon CP, Krug-Gourley S, Wittes J, Trivedi T, Tarka E, Wallentin L. Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease. Am Heart J. 2010 Oct; 160(4):655-61.
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Hsia CC, Huang FL, Lin CH, Shen LH, Wang HE. The preparation and biological characterization of a new HL91-derivative for hypoxic imaging on stroke mice. Appl Radiat Isot. 2010 Sep; 68(9):1610-5.
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Spichty M, Taly A, Hagn F, Kessler H, Barluenga S, Winssinger N, Karplus M. The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts. Biophys Chem. 2009 Aug; 143(3):111-23.
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Mikkelsen MD, Fuller VL, Hansen BG, Nafisi M, Olsen CE, Nielsen HB, Halkier BA. Controlled indole-3-acetaldoxime production through ethanol-induced expression of CYP79B2. Planta. 2009 May; 229(6):1209-17.
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Degli Esposti M, Tour J, Ouasti S, Ivanova S, Matarrese P, Malorni W, Khosravi-Far R. Fas death receptor enhances endocytic membrane traffic converging into the Golgi region. Mol Biol Cell. 2009 Jan; 20(2):600-15.
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