 Norfloxacin
"Norfloxacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
| Descriptor ID |
D009643
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| MeSH Number(s) |
D03.438.810.835.322.374
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| Concept/Terms |
MK-0366- MK-0366
- MK 0366
- MK0366
- MK366
- MK-366
- MK 366
Noroxin- Noroxin
- Merck Brand of Norfloxacin
- Norfloxacin Merck Brand
AM-0715- AM-0715
- AM 0715
- AM0715
- AM-715
- AM 715
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Below are MeSH descriptors whose meaning is more general than "Norfloxacin".
Below are MeSH descriptors whose meaning is more specific than "Norfloxacin".
This graph shows the total number of publications written about "Norfloxacin" by people in Harvard Catalyst Profiles by year, and whether "Norfloxacin" was a major or minor topic of these publication.
Below are the most recent publications written about "Norfloxacin" by people in Profiles.
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Truong-Bolduc QC, Hooper DC. Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus. J Bacteriol. 2010 May; 192(10):2525-34.
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Truong-Bolduc QC, Ding Y, Hooper DC. Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus. J Bacteriol. 2008 Nov; 190(22):7375-81.
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Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ. A common mechanism of cellular death induced by bactericidal antibiotics. Cell. 2007 Sep 7; 130(5):797-810.
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DeMarco CE, Cushing LA, Frempong-Manso E, Seo SM, Jaravaza TA, Kaatz GW. Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus. Antimicrob Agents Chemother. 2007 Sep; 51(9):3235-9.
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Tavío MM, Vila J, Perilli M, Casañas LT, Maciá L, Amicosante G, Jiménez de Anta MT. Enhanced active efflux, repression of porin synthesis and development of Mar phenotype by diazepam in two enterobacteria strains. J Med Microbiol. 2004 Nov; 53(Pt 11):1119-22.
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Tavío MM, Perilli M, Vila J, Becerro P, Casañas L, Amicosante G, Jiménez de Anta MT. Salicylate decreases production of AmpC type beta-lactamases and increases susceptibility to beta-lactams in a Morganella morganii clinical isolate. FEMS Microbiol Lett. 2004 Sep 1; 238(1):139-44.
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Morel C, Stermitz FR, Tegos G, Lewis K. Isoflavones as potentiators of antibacterial activity. J Agric Food Chem. 2003 Sep 10; 51(19):5677-9.
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Yen ZS, Davis MA, Chen SC, Chen WJ. A cost-effectiveness analysis of treatment strategies for acute uncomplicated pyelonephritis in women. Acad Emerg Med. 2003 Apr; 10(4):309-14.
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Stermitz FR, Scriven LN, Tegos G, Lewis K. Two flavonols from Artemisa annua which potentiate the activity of berberine and norfloxacin against a resistant strain of Staphylococcus aureus. Planta Med. 2002 Dec; 68(12):1140-1.
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Schaeffer AJ. The expanding role of fluoroquinolones. Am J Med. 2002 Jul 8; 113 Suppl 1A:45S-54S.
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