 Muscimol
"Muscimol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
| Descriptor ID |
D009118
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| MeSH Number(s) |
D03.383.129.462.470 D23.946.587.587
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscimol".
Below are MeSH descriptors whose meaning is more specific than "Muscimol".
This graph shows the total number of publications written about "Muscimol" by people in Harvard Catalyst Profiles by year, and whether "Muscimol" was a major or minor topic of these publication.
Below are the most recent publications written about "Muscimol" by people in Profiles.
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Wheeler DW, Thompson AJ, Corletto F, Reckless J, Loke JC, Lapaque N, Grant AJ, Mastroeni P, Grainger DJ, Padgett CL, O'Brien JA, Miller NG, Trowsdale J, Lummis SC, Menon DK, Beech JS. Anaesthetic impairment of immune function is mediated via GABA(A) receptors. PLoS One. 2011; 6(2):e17152.
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Chamberlin NL, Eikermann M, Fassbender P, White DP, Malhotra A. Genioglossus premotoneurons and the negative pressure reflex in rats. J Physiol. 2007 Mar 1; 579(Pt 2):515-26.
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Li GD, Chiara DC, Sawyer GW, Husain SS, Olsen RW, Cohen JB. Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog. J Neurosci. 2006 Nov 8; 26(45):11599-605.
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Gompf HS, Irwin RP, Allen CN. Retrograde suppression of GABAergic currents in a subset of SCN neurons. Eur J Neurosci. 2006 Jun; 23(12):3209-16.
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Glykys J, Mody I. Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice. J Neurophysiol. 2006 May; 95(5):2796-807.
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Goussakov I, Chartoff EH, Tsvetkov E, Gerety LP, Meloni EG, Carlezon WA, Bolshakov VY. LTP in the lateral amygdala during cocaine withdrawal. Eur J Neurosci. 2006 Jan; 23(1):239-50.
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Li S, Varga V, Sik A, Kocsis B. GABAergic control of the ascending input from the median raphe nucleus to the limbic system. J Neurophysiol. 2005 Oct; 94(4):2561-74.
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Halpern JH. Hallucinogens and dissociative agents naturally growing in the United States. Pharmacol Ther. 2004 May; 102(2):131-8.
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Tonkiss J, Shultz PL, Bonnie KE, Hudson JL, Duran P, Galler JR. Spatial learning deficits induced by muscimol and CL218,872: lack of effect of prenatal malnutrition. Nutr Neurosci. 2003 Dec; 6(6):379-87.
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Kohane DS, Holmes GL, Chau Y, Zurakowski D, Langer R, Cha BH. Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures. Epilepsia. 2002 Dec; 43(12):1462-8.
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