 Mefloquine
"Mefloquine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects.
| Descriptor ID |
D015767
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| MeSH Number(s) |
D03.438.810.410
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| Concept/Terms |
Lariam- Lariam
- Hoffmann-La Roche Brand of Mefloquine Hydrochloride
- Hoffmann La Roche Brand of Mefloquine Hydrochloride
- Roche Brand of Mefloquine Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Mefloquine".
Below are MeSH descriptors whose meaning is more specific than "Mefloquine".
This graph shows the total number of publications written about "Mefloquine" by people in Harvard Catalyst Profiles by year, and whether "Mefloquine" was a major or minor topic of these publication.
Below are the most recent publications written about "Mefloquine" by people in Profiles.
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Gbotosho GO, Happi CT, Lawal O, Sijuade A, Sowunmi A, Oduola A. A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans. Malar J. 2012; 11:59.
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McGuire JL, Fridman V, Wüthrich C, Koralnik IJ, Jacobs D. Progressive multifocal leukoencephalopathy associated with isolated CD8+ T-lymphocyte deficiency mimicking tumefactive MS. J Neurovirol. 2011 Oct; 17(5):500-3.
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Sowunmi A, Gbotosho GO, Happi CT, Folarin O, Okuboyejo T, Michael O, Fatunmbi B. Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment. Am J Ther. 2011 May; 18(3):190-7.
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Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr; 7(4):e1001383.
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Veiga MI, Ferreira PE, Schmidt BA, Ribacke U, Björkman A, Tichopad A, Gil JP. Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression. PLoS One. 2010; 5(8):e12408.
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Sowunmi A, Nkogho OO, Okuboyejo TM, Gbotosho GO, Happi CT, Adewoye EO. Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children. Malar J. 2009; 8:297.
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Sowunmi A, Gbotosho GO, Happi C, Okuboyejo T, Folarin O, Balogun S, Michael O. Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria. Am J Trop Med Hyg. 2009 Dec; 81(6):979-86.
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Prudêncio M, Derbyshire ET, Marques CA, Krishna S, Mota MM, Staines HM. Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells. Cell Microbiol. 2009 Oct; 11(10):1492-501.
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Cummings DM, Yamazaki I, Cepeda C, Paul DL, Levine MS. Neuronal coupling via connexin36 contributes to spontaneous synaptic currents of striatal medium-sized spiny neurons. J Neurosci Res. 2008 Aug 1; 86(10):2147-58.
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Faye B, Ndiaye JL, Ndiaye D, Dieng Y, Faye O, Gaye O. Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. Malar J. 2007; 6:80.
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