 Estradiol
"Estradiol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
| Descriptor ID |
D004958
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| MeSH Number(s) |
D04.808.365.415.248 D06.472.334.851.437.500
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| Concept/Terms |
Estradiol- Estradiol
- 17 beta-Oestradiol
- 17 beta Oestradiol
- Estradiol-17beta
- Estradiol 17beta
- Oestradiol
- 17 beta-Estradiol
- 17 beta Estradiol
- Estradiol-17 beta
- Estradiol 17 beta
Ovocyclin- Ovocyclin
- Orion Brand of Estradiol
- Estradiol Orion Brand
Vivelle- Vivelle
- Novartis Pharmaceuticals Brand of Estradiol
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Below are MeSH descriptors whose meaning is more general than "Estradiol".
Below are MeSH descriptors whose meaning is more specific than "Estradiol".
This graph shows the total number of publications written about "Estradiol" by people in Harvard Catalyst Profiles by year, and whether "Estradiol" was a major or minor topic of these publication.
Below are the most recent publications written about "Estradiol" by people in Profiles.
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Sun H, Si C, Bian Q, Chen X, Chen L, Wang X. Developing in vitro reporter gene assays to assess the hormone receptor activities of chemicals frequently detected in drinking water. J Appl Toxicol. 2012 Aug; 32(8):635-41.
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Wildman RP, Tepper PG, Crawford S, Finkelstein JS, Sutton-Tyrrell K, Thurston RC, Santoro N, Sternfeld B, Greendale GA. Do changes in sex steroid hormones precede or follow increases in body weight during the menopause transition? Results from the Study of Women's Health Across the Nation. J Clin Endocrinol Metab. 2012 Sep; 97(9):E1695-704.
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Prescott J, Thompson DJ, Kraft P, Chanock SJ, Audley T, Brown J, Leyland J, Folkerd E, Doody D, Hankinson SE, Hunter DJ, Jacobs KB, Dowsett M, Cox DG, Easton DF, De Vivo I. Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. PLoS One. 2012; 7(6):e37815.
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Tepper PG, Randolph JF, McConnell DS, Crawford SL, El Khoudary SR, Joffe H, Gold EB, Zheng H, Bromberger JT, Sutton-Tyrrell K. Trajectory clustering of estradiol and follicle-stimulating hormone during the menopausal transition among women in the Study of Women's Health across the Nation (SWAN). J Clin Endocrinol Metab. 2012 Aug; 97(8):2872-80.
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Kuter I, Gee JM, Hegg R, Singer CF, Badwe RA, Lowe ES, Emeribe UA, Anderson E, Sapunar F, Finlay P, Nicholson RI, Bines J, Harbeck N. Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study. Breast Cancer Res Treat. 2012 May; 133(1):237-46.
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Imudia AN, Awonuga AO, Doyle JO, Kaimal AJ, Wright DL, Toth TL, Styer AK. Peak serum estradiol level during controlled ovarian hyperstimulation is associated with increased risk of small for gestational age and preeclampsia in singleton pregnancies after in vitro fertilization. Fertil Steril. 2012 Jun; 97(6):1374-9.
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Yin Z, Sada AA, Reslan OM, Narula N, Khalil RA. Increased MMPs expression and decreased contraction in the rat myometrium during pregnancy and in response to prolonged stretch and sex hormones. Am J Physiol Endocrinol Metab. 2012 Jul 1; 303(1):E55-70.
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Thurston RC, El Khoudary SR, Sutton-Tyrrell K, Crandall CJ, Gold EB, Sternfeld B, Joffe H, Selzer F, Matthews KA. Vasomotor symptoms and lipid profiles in women transitioning through menopause. Obstet Gynecol. 2012 Apr; 119(4):753-61.
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Ackerman KE, Skrinar GS, Medvedova E, Misra M, Miller KK. Estradiol levels predict bone mineral density in male collegiate athletes: a pilot study. Clin Endocrinol (Oxf). 2012 Mar; 76(3):339-45.
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Schernhammer ES, Giobbie-Hurder A, Gantman K, Savoie J, Scheib R, Parker LM, Chen WY. A randomized controlled trial of oral melatonin supplementation and breast cancer biomarkers. Cancer Causes Control. 2012 Apr; 23(4):609-16.
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