 Ephrins
"Ephrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signaling proteins that are ligands for the EPH FAMILY RECEPTORS. They are membrane-bound proteins that are attached to the CELL MEMBRANE either through a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR or through a transmembrane domain. Many of the ephrins are considered important intercellular signaling molecules that control morphogenic changes during embryogenesis.
| Descriptor ID |
D036342
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| MeSH Number(s) |
D12.644.276.500 D12.776.467.500 D12.776.543.287 D23.529.500
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| Concept/Terms |
Ephrins- Ephrins
- Eph Receptor Ligands
- Ligands, Eph Receptor
- Receptor Ligands, Eph
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Below are MeSH descriptors whose meaning is more general than "Ephrins".
Below are MeSH descriptors whose meaning is more specific than "Ephrins".
This graph shows the total number of publications written about "Ephrins" by people in Harvard Catalyst Profiles by year, and whether "Ephrins" was a major or minor topic of these publication.
Below are the most recent publications written about "Ephrins" by people in Profiles.
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Patel-Hett S, D'Amore PA. Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol. 2011; 55(4-5):353-63.
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Islam S, Loizides AM, Fialkovich JJ, Grand RJ, Montgomery RK. Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci. 2010 Sep; 55(9):2478-88.
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Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL. Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. J Bone Miner Res. 2009 May; 24(5):775-84.
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Baba A, Akagi K, Takayanagi M, Flanagan JG, Kobayashi T, Hattori M. Fyn tyrosine kinase regulates the surface expression of glycosylphosphatidylinositol-linked ephrin via the modulation of sphingomyelin metabolism. J Biol Chem. 2009 Apr 3; 284(14):9206-14.
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Wybieralska E, Laczna E, Madeja Z. [Role of ephrins in regulation of tumour cell migration]. Postepy Biochem. 2009; 55(2):153-62.
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Luria V, Krawchuk D, Jessell TM, Laufer E, Kania A. Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. Neuron. 2008 Dec 26; 60(6):1039-53.
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Jiao JW, Feldheim DA, Chen DF. Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system. Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25):8778-83.
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Qiu R, Wang X, Davy A, Wu C, Murai K, Zhang H, Flanagan JG, Soriano P, Lu Q. Regulation of neural progenitor cell state by ephrin-B. J Cell Biol. 2008 Jun 16; 181(6):973-83.
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Luria V, Laufer E. Lateral motor column axons execute a ternary trajectory choice between limb and body tissues. Neural Dev. 2007; 2:13.
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Kulkarni RN, Kahn CR. Ephs and ephrins keep pancreatic Beta cells connected. Cell. 2007 Apr 20; 129(2):241-3.
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