 Ephrin-A5
"Ephrin-A5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It has been shown to mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It is found in a variety of adult tissues of BRAIN; HEART; and KIDNEY.
| Descriptor ID |
D036386
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| MeSH Number(s) |
D12.644.276.500.500 D12.776.395.550.448.340 D12.776.467.500.500 D12.776.543.287.500 D12.776.543.484.500.340 D12.776.543.550.418.340 D23.529.500.500
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| Concept/Terms |
Ephrin-A5- Ephrin-A5
- Ephrin A5
- AL-1 Protein
- AL 1 Protein
- RAGS Protein
- LERK-7 Protein
- LERK 7 Protein
- AL-1
- Repulsive Axon Guidance Signal Protein
- REK7 Ligand AL-1
- REK7 Ligand AL 1
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Below are MeSH descriptors whose meaning is more general than "Ephrin-A5".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-A5".
This graph shows the total number of publications written about "Ephrin-A5" by people in Harvard Catalyst Profiles by year, and whether "Ephrin-A5" was a major or minor topic of these publication.
Below are the most recent publications written about "Ephrin-A5" by people in Profiles.
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Chen Y, Flanagan JG. Follow your nose: axon pathfinding in olfactory map formation. Cell. 2006 Dec 1; 127(5):881-4.
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Ellsworth CA, Lyckman AW, Feldheim DA, Flanagan JG, Sur M. Ephrin-A2 and -A5 influence patterning of normal and novel retinal projections to the thalamus: conserved mapping mechanisms in visual and auditory thalamic targets. J Comp Neurol. 2005 Jul 25; 488(2):140-51.
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Pfeiffenberger C, Cutforth T, Woods G, Yamada J, Rentería RC, Copenhagen DR, Flanagan JG, Feldheim DA. Ephrin-As and neural activity are required for eye-specific patterning during retinogeniculate mapping. Nat Neurosci. 2005 Aug; 8(8):1022-7.
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Hansen MJ, Dallal GE, Flanagan JG. Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibition. Neuron. 2004 Jun 10; 42(5):717-30.
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Niederkofler V, Salie R, Sigrist M, Arber S. Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28; 24(4):808-18.
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Bach H, Feldheim DA, Flanagan JG, Scalia F. Persistence of graded EphA/Ephrin-A expression in the adult frog visual system. J Comp Neurol. 2003 Dec 22; 467(4):549-65.
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Dufour A, Seibt J, Passante L, Depaepe V, Ciossek T, Frisén J, Kullander K, Flanagan JG, Polleux F, Vanderhaeghen P. Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes. Neuron. 2003 Jul 31; 39(3):453-65.
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Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15; 22(8):1811-23.
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Lyckman AW, Jhaveri S, Feldheim DA, Vanderhaeghen P, Flanagan JG, Sur M. Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant. J Neurosci. 2001 Oct 1; 21(19):7684-90.
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Prakash N, Vanderhaeghen P, Cohen-Cory S, Frisén J, Flanagan JG, Frostig RD. Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging. J Neurosci. 2000 Aug 1; 20(15):5841-7.
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