 Ephrin-A1
"Ephrin-A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
| Descriptor ID |
D036382
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| MeSH Number(s) |
D12.644.276.500.100 D12.776.395.550.448.300 D12.776.467.500.100 D12.776.543.287.100 D12.776.543.484.500.300 D12.776.543.550.418.300 D23.529.500.100
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| Concept/Terms |
Ephrin-A1- Ephrin-A1
- Ephrin A1
- Eck Ligand
- Ligand, Eck
- LERK-1 Protein
- LERK 1 Protein
- Endothelium Secreted Protein B61
- Epl1 Protein
- EPLG1
- B61 Secreted Protein, Endothelium
- Eck RPTK Ligand
- RPTK Ligand, Eck
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Below are MeSH descriptors whose meaning is more general than "Ephrin-A1".
Below are MeSH descriptors whose meaning is more specific than "Ephrin-A1".
This graph shows the total number of publications written about "Ephrin-A1" by people in Harvard Catalyst Profiles by year, and whether "Ephrin-A1" was a major or minor topic of these publication.
Below are the most recent publications written about "Ephrin-A1" by people in Profiles.
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Goichberg P, Bai Y, D'Amario D, Ferreira-Martins J, Fiorini C, Zheng H, Signore S, del Monte F, Ottolenghi S, D'Alessandro DA, Michler RE, Hosoda T, Anversa P, Kajstura J, Rota M, Leri A. The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction. Circ Res. 2011 Apr 29; 108(9):1071-83.
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Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nat Neurosci. 2010 Feb; 13(2):163-72.
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Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, Chen J. Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Mol Cell Biol. 2006 Jul; 26(13):4830-42.
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Barrier A, Olaya N, Chiappini F, Roser F, Scatton O, Artus C, Franc B, Dudoit S, Flahault A, Debuire B, Azoulay D, Lemoine A. Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion. FASEB J. 2005 Oct; 19(12):1617-26.
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Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness. Biochem Biophys Res Commun. 2004 Aug 6; 320(4):1096-102.
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Shamah SM, Lin MZ, Goldberg JL, Estrach S, Sahin M, Hu L, Bazalakova M, Neve RL, Corfas G, Debant A, Greenberg ME. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Cell. 2001 Apr 20; 105(2):233-44.
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Rosenberg IM, Göke M, Kanai M, Reinecker HC, Podolsky DK. Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function. Am J Physiol. 1997 Oct; 273(4 Pt 1):G824-32.
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