 Diazepam
"Diazepam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
| Descriptor ID |
D003975
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| MeSH Number(s) |
D03.438.079.080.070.216
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| Concept/Terms |
Diazepam- Diazepam
- 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
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Below are MeSH descriptors whose meaning is more general than "Diazepam".
Below are MeSH descriptors whose meaning is more specific than "Diazepam".
This graph shows the total number of publications written about "Diazepam" by people in Harvard Catalyst Profiles by year, and whether "Diazepam" was a major or minor topic of these publication.
Below are the most recent publications written about "Diazepam" by people in Profiles.
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Marowsky A, Rudolph U, Fritschy JM, Arand M. Tonic inhibition in principal cells of the amygdala: a central role for a3 subunit-containing GABAA receptors. J Neurosci. 2012 Jun 20; 32(25):8611-9.
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Sánchez Fernández I, Hadjiloizou S, Eksioglu Y, Peters JM, Takeoka M, Tas E, Abdelmoumen I, Rotenberg A, Kothare SV, Riviello JJ, Loddenkemper T. Short-term response of sleep-potentiated spiking to high-dose diazepam in electric status epilepticus during sleep. Pediatr Neurol. 2012 May; 46(5):312-8.
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Chaleff S, Hurwitz CA, Chang M, Dahl G, Alonzo TA, Weinstein H. Phase II study of 2-chlorodeoxyadenosine plus idarubicin for children with acute myeloid leukaemia in first relapse: a paediatric oncology group study. Br J Haematol. 2012 Mar; 156(5):649-55.
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Tavío MM, Aquili VD, Fàbrega A, Vila J, Poveda JB. Overexpression of the quorum-sensing regulator sdiA and soxS is involved in low-level multidrug resistance induced in Escherichia coli AG100 by haloperidol, diazepam and NaCl. Int J Antimicrob Agents. 2012 Jan; 39(1):91-3.
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Jeon D, Chu K, Lee ST, Jung KH, Kang KM, Ban JJ, Kim S, Seo JS, Won CH, Kim M, Lee SK, Roh JK. A cell-free extract from human adipose stem cells protects mice against epilepsy. Epilepsia. 2011 Sep; 52(9):1617-26.
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Witschi R, Punnakkal P, Paul J, Walczak JS, Cervero F, Fritschy JM, Kuner R, Keist R, Rudolph U, Zeilhofer HU. Presynaptic alpha2-GABAA receptors in primary afferent depolarization and spinal pain control. J Neurosci. 2011 Jun 1; 31(22):8134-42.
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Birkett MA, Shinday NM, Kessler EJ, Meyer JS, Ritchie S, Rowlett JK. Acute anxiogenic-like effects of selective serotonin reuptake inhibitors are attenuated by the benzodiazepine diazepam in BALB/c mice. Pharmacol Biochem Behav. 2011 Jun; 98(4):544-51.
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Kinsey SG, O'Neal ST, Long JZ, Cravatt BF, Lichtman AH. Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay. Pharmacol Biochem Behav. 2011 Mar; 98(1):21-7.
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Smith KS, Meloni EG, Myers KM, Van't Veer A, Carlezon WA, Rudolph U. Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice. Psychopharmacology (Berl). 2011 Feb; 213(4):697-706.
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Fischer BD, Licata SC, Edwankar RV, Wang ZJ, Huang S, He X, Yu J, Zhou H, Johnson EM, Cook JM, Furtmüller R, Ramerstorfer J, Sieghart W, Roth BL, Majumder S, Rowlett JK. Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure. Neuropharmacology. 2010 Dec; 59(7-8):612-8.
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