 Clathrin
"Clathrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
| Descriptor ID |
D002966
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| MeSH Number(s) |
D12.776.543.990.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clathrin".
Below are MeSH descriptors whose meaning is more specific than "Clathrin".
This graph shows the total number of publications written about "Clathrin" by people in Harvard Catalyst Profiles by year, and whether "Clathrin" was a major or minor topic of these publication.
Below are the most recent publications written about "Clathrin" by people in Profiles.
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Cocucci E, Aguet F, Boulant S, Kirchhausen T. The first five seconds in the life of a clathrin-coated pit. Cell. 2012 Aug 3; 150(3):495-507.
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Bai M, Pang X, Lou J, Zhou Q, Zhang K, Ma J, Li J, Sun F, Hsu VW. Mechanistic insights into regulated cargo binding by ACAP1 protein. J Biol Chem. 2012 Aug 17; 287(34):28675-85.
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Vitaliano GD, Vitaliano F, Rios JD, Renshaw PF, Teicher MH. New clathrin-based nanoplatforms for magnetic resonance imaging. PLoS One. 2012; 7(5):e35821.
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Fukumatsu M, Ogawa M, Arakawa S, Suzuki M, Nakayama K, Shimizu S, Kim M, Mimuro H, Sasakawa C. Shigella targets epithelial tricellular junctions and uses a noncanonical clathrin-dependent endocytic pathway to spread between cells. Cell Host Microbe. 2012 Apr 19; 11(4):325-36.
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Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA. Differential, phosphorylation dependent trafficking of AQP2 in LLC-PK1 cells. PLoS One. 2012; 7(2):e32843.
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Cureton DK, Harbison CE, Cocucci E, Parrish CR, Kirchhausen T. Limited transferrin receptor clustering allows rapid diffusion of canine parvovirus into clathrin endocytic structures. J Virol. 2012 May; 86(9):5330-40.
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Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, DeJager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S. Functional links between Aß toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 2; 334(6060):1241-5.
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Nunez D, Antonescu C, Mettlen M, Liu A, Schmid SL, Loerke D, Danuser G. Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources. Traffic. 2011 Dec; 12(12):1868-78.
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Boulant S, Kural C, Zeeh JC, Ubelmann F, Kirchhausen T. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol. 2011 Sep; 13(9):1124-31.
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Ivanovic T, Boulant S, Ehrlich M, Demidenko AA, Arnold MM, Kirchhausen T, Nibert ML. Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking. Traffic. 2011 Sep; 12(9):1179-95.
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