 Caffeine
"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
| Descriptor ID |
D002110
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| MeSH Number(s) |
D03.132.960.175 D03.438.759.758.824.175
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| Concept/Terms |
Dexitac- Dexitac
- Republic Drug Brand of Caffeine
Vivarin- Vivarin
- GlaxoSmithKline Brand of Caffeine
Quick-Pep- Quick-Pep
- Thompson Brand 2 of Caffeine
No Doz- No Doz
- Bristol-Myers Squibb Brand of Caffeine
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Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in Harvard Catalyst Profiles by year, and whether "Caffeine" was a major or minor topic of these publication.
Below are the most recent publications written about "Caffeine" by people in Profiles.
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Josse AR, Da Costa LA, Campos H, El-Sohemy A. Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption. Am J Clin Nutr. 2012 Sep; 96(3):665-71.
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Postuma RB, Lang AE, Munhoz RP, Charland K, Pelletier A, Moscovich M, Filla L, Zanatta D, Rios Romenets S, Altman R, Chuang R, Shah B. Caffeine for treatment of Parkinson disease: a randomized controlled trial. Neurology. 2012 Aug 14; 79(7):651-8.
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Schwarzschild MA. Caffeine in Parkinson disease: better for cruise control than snooze patrol? Neurology. 2012 Aug 14; 79(7):616-8.
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Song F, Qureshi AA, Han J. Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin. Cancer Res. 2012 Jul 1; 72(13):3282-9.
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Mostofsky E, Rice MS, Levitan EB, Mittleman MA. Habitual coffee consumption and risk of heart failure: a dose-response meta-analysis. Circ Heart Fail. 2012 Jul 1; 5(4):401-5.
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Jiwani AZ, Rhee DJ, Brauner SC, Gardiner MF, Chen TC, Shen LQ, Chen SH, Grosskreutz CL, Chang KK, Kloek CE, Greenstein SH, Borboli-Gerogiannis S, Pasquale DL, Chaudhry S, Loomis S, Wiggs JL, Pasquale LR, Turalba AV. Effects of caffeinated coffee consumption on intraocular pressure, ocular perfusion pressure, and ocular pulse amplitude: a randomized controlled trial. Eye (Lond). 2012 Aug; 26(8):1122-30.
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Yen M, Ewald MB. Toxicity of weight loss agents. J Med Toxicol. 2012 Jun; 8(2):145-52.
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Townsend MK, Resnick NM, Grodstein F. Caffeine intake and risk of urinary incontinence progression among women. Obstet Gynecol. 2012 May; 119(5):950-7.
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Wolk BJ, Ganetsky M, Babu KM. Toxicity of energy drinks. Curr Opin Pediatr. 2012 Apr; 24(2):243-51.
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Li W, Han J, Qureshi AA. No association between coffee and caffeine intake and risk of psoriasis in US women. Arch Dermatol. 2012 Mar; 148(3):395-7.
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