Contact Us News RSS Login

Harvard Catalyst - The Harvard Clinical and Translational Science Center
  1. People
    1. Overview
    2. Grant Central
    3. Medvane
    4. Profiles
  2. Learning
    1. Overview
    2. Colloquium Series
    3. Conferences and Seminars
    4. Dean's Symposium
    5. Leder Human Biology
    6. Biomedical Informatics Training
    7. Biostatistics Training
    8. Clinical Investigator Training Program
    9. Scholars in Clinical Science
    10. KL2 Medical Research Investigator Training
    11. Introduction to Clinical Investigation
    12. Biostatistics Seminar Series
    13. Genetics Courses
    14. Imaging Courses
  3. Resources
    1. Overview
    2. Pilot Funding
    3. AEGIS Influenza
    4. Atlas
    5. Community-Based Participatory Research
    6. Community Connect to Research
    7. Consulting Programs
    8. Core Facilities
    9. HarvardTrials
    10. Health Disparities Research Program
    11. In/Outpatient Resources
    12. Laboratory for Innovative Translational Technologies
    13. Law and Health Policy
    14. Medications and Society
    15. Pathology Specimen Locator
    16. SHRINE
    17. Webdash
Find
People

Profiles

Read About Profiles -- the Harvard Catalyst's social networking site.
Find information about people's institutions in the Atlas.

Deborah Jean Culley, M.D.

 
Title
Assistant Professor of Anaesthesia
Institution
Brigham and Women's Hospital
Department
Anaesthesia
Address
Brigham and Women's Hospital
Anesthesiology, Perioperative & Pain Mgt
75 Francis St
Boston, MA 02115
Telephone
617/732-7330
Fax
617/730-2813
Publications
1. Culley DJ, Baxter M, Yukhananov R, Crosby G. The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg. 2003 Apr; 96(4):1004-9, table of contents.
2. Culley DJ, Baxter MG, Yukhananov R, Crosby G. Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats. Anesthesiology. 2004 Feb; 100(2):309-14.
3. Tran T, Culley DJ, Crosby G. Hemorrhagic stroke after spinal anesthesia and minor surgery. J Clin Anesth. 2004 Jun; 16(4):293-5.
4. Culley DJ, Baxter MG, Crosby CA, Yukhananov R, Crosby G. Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg. 2004 Nov; 99(5):1393-7; table of contents.
5. Crosby C, Culley DJ, Baxter MG, Yukhananov R, Crosby G. Spatial memory performance 2 weeks after general anesthesia in adult rats. Anesth Analg. 2005 Nov; 101(5):1389-92.
6. Culley DJ, Loguinov A, Yukhananov R, Crosby G. General anesthesia does not reduce life expectancy in aged rats. Anesth Analg. 2006 Mar; 102(3):956-9.
7. Xie Z, Dong Y, Maeda U, Alfille P, Culley DJ, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology. 2006 May; 104(5):988-94.
8. Culley DJ, Yukhananov RY, Xie Z, Gali RR, Tanzi RE, Crosby G. Altered hippocampal gene expression 2 days after general anesthesia in rats. Eur J Pharmacol. 2006 Nov 7; 549(1-3):71-8.
9. Marcantonio ER, Rudolph JL, Culley D, Crosby G, Alsop D, Inouye SK. Serum biomarkers for delirium. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1281-6.
10. Xie Z, Dong Y, Maeda U, Moir R, Inouye SK, Culley DJ, Crosby G, Tanzi RE. Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia. J Gerontol A Biol Sci Med Sci. 2006 Dec; 61(12):1300-6.
11. Culley DJ, Crosby G, Xie Z, Vacanti CA, Kitz RJ, Zapol WM. Career National Institutes of Health funding and scholarship of chairpersons of academic departments of anesthesiology and surgery. Anesthesiology. 2007 Apr; 106(4):836-42.
12. Culley DJ, Raghavan SV, Waly M, Baxter MG, Yukhananov R, Deth RC, Crosby G. Nitrous oxide decreases cortical methionine synthase transiently but produces lasting memory impairment in aged rats. Anesth Analg. 2007 Jul; 105(1):83-8.
13. Culley DJ, Xie Z, Crosby G. General anesthetic-induced neurotoxicity: an emerging problem for the young and old? Curr Opin Anaesthesiol. 2007 Oct; 20(5):408-13.
14. Zhang B, Dong Y, Zhang G, Moir RD, Xia W, Yue Y, Tian M, Culley DJ, Crosby G, Tanzi RE, Xie Z. The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem. 2008 May 2; 283(18):11866-75.
15. Zhang G, Dong Y, Zhang B, Ichinose F, Wu X, Culley DJ, Crosby G, Tanzi RE, Xie Z. Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci. 2008 Apr 23; 28(17):4551-60.
 
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact Human Resources at faculty_serviceshms.harvard.edu.