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Adam Wright, PH.D.

 
Title
Instructor in Medicine
Institution
Brigham and Women's Hospital
Department
Medicine
Division
General Medicine
Address
Brigham and Women's Hospital
General Medicine
1620 Tremont St
Boston, MA 02120
Telephone
617/732-7063
Fax
617/732-7072
Email
Email Address
Narrative
The overarching goal of my research is to improve quality of care and increase patient safety through innovative work in clinical systems and related areas of medical informatics. To this end, my research has two principal focuses: clinical decision support and mining large warehouses of clinical data.

My clinical decision support research primarily focuses on architectures for sharing decision support content across sites. I have developed an architecture, called SANDS, for syndicating decision support content across networks. Early results are positive, and in my current work, I am extending the architecture to work at more sites, and bringing it into real-world use.

In addition to my work on architectures for decision support, I conduct a variety of other projects. Many of these are listed elsewhere in this CV, but I will highlight a few here:

Data mining for decision support: I have been applying data mining techniques to large clinical datasets in order to automatically develop decision support content, such as order sets and corollary orders. I am the PI of a funded study applying these techniques to the domain of clinical problem lists.

Personal Health Records: I have a special interest in the privacy aspects of personal health records, particularly technical issues such as encryption and security.

Quality-CPOE link: I am leading a project to quantitatively explore the link between CPOE and quality of care. We are collaborating with HIMSS Analytics, the Leapfrog Group and HealthGrades on this work.

Applied guideline sharing: I am the Partners site lead for an AHRQ-funded project to share guidelines and clinical decision support content across six sites in the United States.
Publications
1. Chow K, Wright A, Lai K. Characterization of Java Workloads by Principal Components Analysis and Indirect Branches. Proc ACM/IEEE Int Symp on Microarchitecture Workshop on Workload Characterization. 1998.
2. Wright A. Visualizing Biological Networks through Selective Reduction and Force Direction. Proc Biomed Comp at Stanford. 2004.
3. Wright A, Ricciardi TN, Zwick M. Application of information-theoretic data mining techniques in a national ambulatory practice outcomes research network. AMIA Annu Symp Proc. 2005; 829-33.
4. Osheroff JA, Teich JM, Middleton B, Steen EB, Wright A, Detmer DE. A Roadmap for National Action on Clinical Decision Support. National Expert Consensus Panel Report. 2006.
5. Wright A, Sittig DF. Automated development of order sets and corollary orders by data mining in an ambulatory computerized physician order entry system. AMIA Annu Symp Proc. 2006; 819-23.
6. Wright A, Sittig DF. Association Rule Mining Techniques for Corollary Order Generation. AMIA Spring Congress Proc. 2006.
7. Wright A, Sittig DF. SANDS: An Architecture for Clinical Decision Support in a National Health Information Network. AMIA Annu Symp Proc. 2007; 573-7.
8. Osheroff JA, Teich JM, Middleton B, Steen EB, Wright A, Detmer DE. A roadmap for national action on clinical decision support. J Am Med Inform Assoc. 2007 Mar-Apr; 14(2):141-5.
9. Wright A, Sittig DF. Security threat posed by USB-based personal health records. Ann Intern Med. 2007 Feb 20; 146(4):314-5.
10. Wright A, Goldberg H, Hongsermeier T, Middleton B. A description and functional taxonomy of rule-based decision support content at a large integrated delivery network. J Am Med Inform Assoc. 2007 Jul-Aug; 14(4):489-96.
11. Wright A, Sittig DF. Encryption characteristics of two USB-based personal health record devices. J Am Med Inform Assoc. 2007 Jul-Aug; 14(4):397-9.
12. Wright A. An Architecture for Clinical Decision Support in a National Health Information Network [Dissertation]. 2007.
13. Sittig DF, Wright A, Osheroff JA, Middleton B, Teich JM, Ash JS, Campbell E, Bates DW. Grand challenges in clinical decision support. J Biomed Inform. 2008 Apr; 41(2):387-92.
14. Wright A, Sittig DF. SANDS: an architecture for clinical decision support in a National Health Information Network. AMIA Annu Symp Proc. 2007; 816-20.
15. Chen ES, Wright A, Maloney FL, Van Putten C, Paterno MD, Goldberg HS. Enhancing Clinical Problem Lists Through Data Mining and Natural Language Processing (accepted). 2008.
16. Hersh W, Wright A. What Workforce is Needed to Implement the Health Information Technology Agenda? Analysis from the HIMSS Analytics Database (accepted). AMIA Annu Symp Proc. 2008.
17. McGlinchey EA, Wright A, Poon EG, Jenter CA, Bates DW, Simon SR. Ability to Perform Registry Functions Among Practices With and Without Electronic Health Records (accepted). American Medical Informatics Association Annual Symposium. 2008.
18. McGlinchey EA, Wright A, Poon EG, Jenter CA, Bates DW, Simon SR. Ability to Perform Registry Functions Among Practices With and Without Electronic Health Records. Society for General Internal Medicine Annual Meeting. 2008.
19. Paterno MD, Schaeffer M, Van Putten C, Wright A, Chen ES, Goldberg HS. Challenges in Creating an Enterprise Clinical Rules Service (accepted). American Medical Informatics Association Annual Symposium. 2008.
20. Wright A, Bates DW, Middleton B, Thomas SM, Sittig DF. Web 2.0 and Clinical Decision Support (accepted). AMIA Annu Symp Proc. 2008.
21. Wright A, Poon EG, Wald J, Schnipper JL, Grant R, Gandhi TK, Volk LA, Bloom A, Williams DH, Gardner K, Epstein M, Nelson L, Businger A, Li Q, Bates DW, Middleton B. Effectiveness of Health Maintenance Reminders Provided Directly to Patients (accepted). American Medical Informatics Association Annual Symposium. 2008.
22. Wright A. Clinical Decision Support. Liu L and Özsu MT, eds. Encyclopedia of Database Systems. 2008.
23. Wright A, Sittig DF. SANDS: A service-oriented architecture for clinical decision support in a National Health Information Network. J Biomed Inform. 2008 Mar 14.
24. Wright A, Sittig DF. A four-phase model of the evolution of clinical decision support architectures. Int J Med Inform. 2008 Mar 18.
25. Wright A, Sittig DF. A framework and model for evaluating clinical decision support architectures. J Biomed Inform. 2008 Mar 25.
26. Wright A, Sittig DF. Book Review: How Doctors Think. Int J Med Inform. 2008; 77(4):287-9.
27. Wright A, Sittig DF. A four-phase model of the evolution of clinical decision support architectures. Int J Med Inform. 2008; in press..
28. Wright A, Sittig DF. Framework and Model for Evaluating Clinical Decision Support Architectures. J Biomed Inform. 2008; in press.
29. Wright A, Sittig DF. SANDS: A Service-Oriented Architecture for Clinical Decision Support in a National Health Information Network. J Biomed Inform. 2008; in press.
30. Wright A, Bates DW, Middleton B, Hongsermeier T, Kashyap V, Thomas SM, Sittig DF. Creating and sharing clinical decision support content with Web 2.0: Issues and examples. J Biomed Inform. 2009 Apr; 42(2):334-46.
31. Chen ES, Wright A, Maloney FL, Van Putten C, Paterno MD, Goldberg HS. Enhancing clinical problem lists through data mining and natural language processing. AMIA Annu Symp Proc. 2008; 901.
32. Hersh W, Wright A. What workforce is needed to implement the health information technology agenda? Analysis from the HIMSS analytics database. AMIA Annu Symp Proc. 2008; 303-7.
33. McGlinchey EA, Wright A, Poon E, Jenter CA, Bates DW, Simon SR. Ability to perform registry functions among practices with and without electronic health records. AMIA Annu Symp Proc. 2008; 1052.
34. Paterno M, Schaeffer M, Van Putten C, Wright A, Chen E, Goldberg H. Challenges in creating an enterprise clinical rules service. AMIA Annu Symp Proc. 2008; 1086.
35. Wright A, Poon E, Wald JS, Schnipper J, Grant R, Gandhi T, Volk L, Bloom A, Williams DH, Gardner K, Epstein M, Nelson L, Businger A, Li Q, Bates DW, Middleton B. Effectiveness of health maintenance reminders provided directly to patients. AMIA Annu Symp Proc. 2008; 1183.
36. Wright A, Sittig DF, Ash JS, Sharma S, Pang JE, Middleton B. Clinical Decision Support Capabilities of Commercially-available Clinical Information Systems. J Am Med Inform Assoc. 2009 Jun 30.
 
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