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Ann Anderson Kiessling, PH.D.

 
Title
Associate Professor of Surgery
Institution
Beth Israel Deaconess Medical Center
Department
Surgery
Address
Harvard Institutes of Medicine
Rm 248
77 Avenue Louis Pasteur
Boston, MA 02115
Telephone
617/667-1083
Fax
781/275-5970
Email
Email Address
Publications
1. Kiessling AA, Weber GH, Deeney AO, Possehl EA, Beaudreau GS. Deoxyribonucleic acid polymerase activity associated with a plasma particulate fraction from patients with chronic lymphocytic leukemia. J Virol. 1971 Feb; 7(2):221-6.
2. Weber GH, Kiessling AA, Beaudreau GS. Deoxyribonucleic acid polymerase activity associated with strain MC29 tumor virus. J Virol. 1971 Feb; 7(2):214-20.
3. Weber GH, Kiessling AA, Beaudreau GS. DNA polymerase activity in homogenates of cells infected with MC29 virus. Biochem Biophys Res Commun. 1971 Mar 19; 42(6):993-9.
4. Kiessling AA, Goulian M. A comparison of the enzymatic responses of the DNA polymerases from four RNA tumor viruses. Biochem Biophys Res Commun. 1976 Aug 23; 71(4):1069-77.
5. Kiessling AA, Goulian M. Detection of reverse transcriptase activity in human cells. Cancer Res. 1979 Jun; 39(6 Pt 1):2062-9.
6. Kiessling AA, Weitlauf HM. DNA polymerase activity in preimplantation mouse embryos. J Exp Zool. 1979 Jun; 208(3):347-54.
7. Weitlauf HM, Kiessling AA. Comparison of overall rates of RNA synthesis in implanting and delayed implanting mouse blastocysts in vitro. Dev Biol. 1980 Jun 1; 77(1):116-29.
8. Kiessling AA, Weitlauf HM. Poly (A) . oligo (dT)-stimulated DNA polymerase activity in preimplantation mouse embryos. J Exp Zool. 1981 Jan; 215(1):117-20.
9. Weitlauf HM, Kiessling AA. Activation of 'delayed implanting' mouse embryos in vitro. J Reprod Fertil Suppl. 1981; 29:191-202.
10. Kiessling AA. Evidence that reverse transcriptase is a component of murine epididymal fluid. Proc Soc Exp Biol Med. 1984 Jun; 176(2):175-82.
11. Kiessling AA, Hughes WH, Blankevoort MR. Superovulation and embryo transfer in the dairy goat. J Am Vet Med Assoc. 1986 Apr 15; 188(8):829-32.
12. Goldman DS, Kiessling AA, Millette CF, Cooper GM, et al. Expression of c-mos RNA in germ cells of male and female mice. Proc Natl Acad Sci U S A. 1987 Jul; 84(13):4509-13.
13. Loutradis D, John D, Kiessling AA. Hypoxanthine causes a 2-cell block in random-bred mouse embryos. Biol Reprod. 1987 Sep; 37(2):311-6.
14. Kiessling AA, Crowell RC, Connell RS. Sperm-associated retroviruses in the mouse epididymis. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8667-71.
15. Borzy MS, Connell RS, Kiessling AA. Detection of human immunodeficiency virus in cell-free seminal fluid. J Acquir Immune Defic Syndr. 1988; 1(5):419-24.
16. Cooper GM, Goldman DS, Kiessling AA, Millette CF, et al. The expression of oncogenes in germ cells. Prog Clin Biol Res. 1988; 267:275-89.
17. John DP, Kiessling AA. Improved pronuclear mouse embryo development over an extended pH range in Ham's F-10 medium without protein. Fertil Steril. 1988 Jan; 49(1):150-5.
18. Kiessling AA, Loutradis D, McShane PM, Jackson KV. Fertilization in trypsin-treated oocytes. Ann N Y Acad Sci. 1988; 541:614-20.
19. Patton PE, Burry KA, Wolf DP, Kiessling AA, Craemer MJ. The use of oral contraceptives to regulate oocyte retrieval. Fertil Steril. 1988 Apr; 49(4):716-8.
20. Han HD, Kiessling AA. In vivo development of transferred mouse embryos conceived in vitro in simple and complex media. Fertil Steril. 1988 Jul; 50(1):159-63.
21. Goldman DS, Kiessling AA, Cooper GM, et al. Post-transcriptional processing suggests that c-mos functions as a maternal message in mouse eggs. Oncogene. 1988 Aug; 3(2):159-62.
22. Montgomery V, Loutradis D, Tulchinsky D, Kiessling A. FSH-induced ovulation in intact and hypophysectomized mice. J Reprod Fertil. 1988 Sep; 84(1):1-6.
23. Trune DR, Kiessling AA. Decreased protein synthesis in cochlear nucleus following developmental auditory deprivation. Use of vascular saline perfusion to improve small tissue sample analysis. Hear Res. 1988 Sep 15; 35(2-3):259-64.
24. Jackson KV, Kiessling AA. Fertilization and cleavage of mouse oocytes exposed to the conditions of human oocyte retrieval for in vitro fertilization. Fertil Steril. 1989 Apr; 51(4):675-81.
25. Kiessling AA. Retroviruses and reproduction. Fertil Steril. 1989 May; 51(5):756-8.
26. Kiessling AA, Crowell R, Fox C. Epididymis is a principal site of retrovirus expression in the mouse. Proc Natl Acad Sci U S A. 1989 Jul; 86(13):5109-13.
27. O'Keefe SJ, Wolfes H, Kiessling AA, Cooper GM, et al. Microinjection of antisense c-mos oligonucleotides prevents meiosis II in the maturing mouse egg. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7038-42.
28. Fissore RA, Jackson KV, Kiessling AA. Mouse zygote development in culture medium without protein in the presence of ethylenediaminetetraacetic acid. Biol Reprod. 1989 Nov; 41(5):835-41.
29. Mehta TS, Kiessling AA. Development potential of mouse embryos conceived in vitro and cultured in ethylenediaminetetraacetic acid with or without amino acids or serum. Biol Reprod. 1990 Oct; 43(4):600-6.
30. Nureddin A, Epsaro E, Kiessling AA. Purines inhibit the development of mouse embryos in vitro. J Reprod Fertil. 1990 Nov; 90(2):455-64.
31. Kiessling AA, Davis HW, Williams CS, Sauter RW, Harrison LW. Development and DNA polymerase activities in cultured preimplantation mouse embryos: comparison with embryos developed in vivo. J Exp Zool. 1991 Apr; 258(1):34-47.
32. O'Keefe SJ, Kiessling AA, Cooper GM. The c-mos gene product is required for cyclin B accumulation during meiosis of mouse eggs. Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17):7869-72.
33. Pal SK, Zinkel SS, Kiessling AA, Cooper GM. c-mos expression in mouse oocytes is controlled by initiator-related sequences immediately downstream of the transcription initiation site. Mol Cell Biol. 1991 Oct; 11(10):5190-6.
34. Lawitts JA, Butler JE, Kiessling AA, Biggers JD. Growth and DNA replication in rabbit blastocysts. Mol Reprod Dev. 1991 Dec; 30(4):320-9.
35. Kiessling AA. Semen transmission of human immunodeficiency virus. Fertil Steril. 1992 Oct; 58(4):667-9.
36. Kiessling AA. HIV in semen. JAMA. 1992 Nov 18; 268(19):2651-2.
37. Fissore R, O'Keefe S, Kiessling AA. Purine-induced block to mouse embryo cleavage is reversed by compounds that elevate cyclic adenosine monophosphate. Biol Reprod. 1992 Dec; 47(6):1105-12.
38. Kiessling AA, Crowell RC, Brettler D, Forsberg A, Wolf B. Human immunodeficiency virus detection and differential leukocyte counts are accurate and safer with formaldehyde-fixed blood. Blood. 1993 Feb 1; 81(3):864-5.
39. Loutradis DC, Kiessling AA, Kallianidis K, Siskos K, Creatsas G, Michalas S, Aravantinos D. A preliminary trial of human zygote culture in Ham's F-10 without hypoxanthine. J Assist Reprod Genet. 1993 May; 10(4):271-5.
40. Pal SK, Crowell R, Kiessling AA, Cooper GM. Expression of proto-oncogenes in mouse eggs and preimplantation embryos. Mol Reprod Dev. 1993 May; 35(1):8-15.
41. Fitzgerald LM, Yin HZ, Kiessling AA. PCR amplification of HIV and cellular DNA sequences in formaldehyde-fixed, immunoreactive white blood cells. Biotechniques. 1993 Jul; 15(1):128-33.
42. Kiessling AA, Yin HZ, Purohit A, Kowal M, Wolf B. Formaldehyde-fixed semen is suitable and safer for leukocyte detection and DNA amplification. Fertil Steril. 1993 Sep; 60(3):576-81.
43. Mehta TS, Kiessling AA. The developmental potential of mouse embryos conceived in Ham's F-10 medium containing ethylenediaminetetraacetic acid. Fertil Steril. 1993 Dec; 60(6):1088-93.
44. Pal SK, Torry D, Serta R, Crowell RC, Seibel MM, Cooper GM, Kiessling AA. Expression and potential function of the c-mos proto-oncogene in human eggs. Fertil Steril. 1994 Mar; 61(3):496-503.
45. Yamauchi N, Kiessling AA, Cooper GM. The Ras/Raf signaling pathway is required for progression of mouse embryos through the two-cell stage. Mol Cell Biol. 1994 Oct; 14(10):6655-62.
46. Loutradis D, Drakakis P, Michalas S, Hatzaki C, Kallianidis K, Aravantinos L, Kiessling AA. The effect of compounds altering the cAMP level on reversing the 2-cell block induced by hypoxanthine in mouse embryos in vitro. Eur J Obstet Gynecol Reprod Biol. 1994 Dec; 57(3):195-9.
47. Drakakis P, Loutradis D, Milingos S, Michalas S, Kallianidis K, Bletsa R, Aravantinos D, Kiessling AA. A preliminary study of the effect of growth hormone on mouse preimplantation embryo development in vitro. Gynecol Obstet Invest. 1995; 40(4):222-6.
48. Seibel MM, Kearnan M, Kiessling A. Parameters that predict success for natural cycle in vitro fertilization-embryo transfer. Fertil Steril. 1995 Jun; 63(6):1251-4.
49. Kiessling AA, Lamparelli N, Yin HZ, Seibel MM, Eyre RC. Semen leukocytes: friends or foes? Fertil Steril. 1995 Jul; 64(1):196-8.
50. Serta RT, Michalopoulos J, Seibel MM, Kiessling AA. The developmental potential of mouse oocytes matured in serum-free culture conditions. Hum Reprod. 1995 Jul; 10(7):1810-5.
51. Kiessling AA, Serta RT, Michalopoulos J. In-vitro maturation of mouse oocytes. Hum Reprod. 1996 Oct; 11(10):2336.
52. Pierce KE, Michalopoulos J, Kiessling AA, Seibel MM, Zilberstein M. Preimplantation development of mouse and human embryos biopsied at cleavage stages using a modified displacement technique. Hum Reprod. 1997 Feb; 12(2):351-6.
53. Byrn RA, Zhang D, Eyre R, McGowan K, Kiessling AA. HIV-1 in semen: an isolated virus reservoir. Lancet. 1997 Oct 18; 350(9085):1141.
54. Kiessling AA, Fitzgerald LM, Zhang D, Chhay H, Brettler D, Eyre RC, Steinberg J, McGowan K, Byrn RA. Human immunodeficiency virus in semen arises from a genetically distinct virus reservoir. AIDS Res Hum Retroviruses. 1998 Apr; 14 Suppl 1:S33-41.
55. Maione B, Lavitrano M, Spadafora C, Kiessling AA. Sperm-mediated gene transfer in mice. Mol Reprod Dev. 1998 Aug; 50(4):406-9.
56. Byrn RA, Kiessling AA. Analysis of human immunodeficiency virus in semen: indications of a genetically distinct virus reservoir. J Reprod Immunol. 1998 Dec; 41(1-2):161-76.
57. Kiessling AA. Expression of human immunodeficiency virus long terminal repeat-coupled genes in early cleaving embryos. J Reprod Immunol. 1998 Dec; 41(1-2):95-104.
58. Eyre RC, Yin HZ, Kiessling AA. Prostate specific antigen is detectable in formalin-fixed semen. BJU Int. 1999 Feb; 83(3):265-8.
59. Eyre RC, Zheng G, Kiessling AA. Multiple drug resistance mutations in human immunodeficiency virus in semen but not blood of a man on antiretroviral therapy. Urology. 2000 Apr; 55(4):591.
60. Kiessling AA, Markoulaki S. Interaction of gametes with exogenous genes: possible opportunities for incorporation into embryonic genome. Mol Reprod Dev. 2000 Jun; 56(2 Suppl):271-4.
61. Kiessling AA. In the stem-cell debate, new concepts need new words. Nature. 2001 Oct 4; 413(6855):453.
62. Green RM, DeVries KO, Bernstein J, Goodman KW, Kaufmann R, Kiessling AA, Levin SR, Moss SL, Tauer CA. Overseeing research on therapeutic cloning: a private ethics board responds to its critics. Hastings Cent Rep. 2002 May-Jun; 32(3):27-33.
63. Okamoto M, Byrn R, Eyre RC, Mullen T, Church P, Kiessling AA. Seminal plasma induces programmed cell death in cultured peripheral blood mononuclear cells. AIDS Res Hum Retroviruses. 2002 Jul 20; 18(11):797-803.
64. Mullen TE, Kiessling RL, Kiessling AA. Tissue-specific populations of leukocytes in semen-producing organs of the normal, hemicastrated, and vasectomized mouse. AIDS Res Hum Retroviruses. 2003 Mar; 19(3):235-43.
65. Kiessling AA. What is an embryo? Conn Law Rev. 2004; 36(4):1051-92.
66. Kiessling AA, Eyre SJ, Desmarais BD. Detection of drug-resistant HIV-1 strains. Methods Mol Biol. 2005; 304:287-313.
67. Kiessling AA. Isolation of human immunodeficiency virus type 1 from semen and vaginal fluids. Methods Mol Biol. 2005; 304:71-86.
68. Kiessling AA. Eggs alone. Nature. 2005 Mar 10; 434(7030):145.
69. Crowell RC, Kiessling AA. Endogenous retrovirus expression in testis and epididymis. Biochem Soc Trans. 2007 Jun; 35(Pt 3):629-33.
70. Kiessling AA, Desmarais BM, Yin HZ, Loverde J, Eyre RC. Detection and identification of bacterial DNA in semen. Fertil Steril. 2008 Nov; 90(5):1744-56.
71. Kiessling AA, Bletsa R, Desmarais B, Mara C, Kallianidis K, Loutradis D. Evidence that human blastomere cleavage is under unique cell cycle control. J Assist Reprod Genet. 2009 Apr; 26(4):187-95.
72. Kiapekou E, Loutradis D, Mastorakos G, Bletsa R, Beretsos P, Zapanti E, Drakakis P, Antsaklis A, Kiessling AA. Effect of PRL on in vitro follicle growth, in vitro oocyte maturation, fertilization and early embryonic development in mice. Cloning Stem Cells. 2009 Jun; 11(2):293-300.
 
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