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Joshua Peter Klein, M.D., PH.D.

 
Title
Instructor in Neurology
Institution
Brigham and Women's Hospital
Department
Neurology
Address
Brigham and Womens Hospital
Neurology
75 Francis St
Boston, MA 02115
Telephone
617/723-7432
Email
Email Address
Awards and Honors
2005 International Student Delegate, Academy of Achievement
2005 M.D./Ph.D. Thesis Prize for outstanding dissertation, Yale Medical School
2009 Dr. Edison H. and Sallie Y. Miyawaki Neuroanatomy Teaching Award, Harvard Medical School
Publications
1. Klein JP, Leete TH, Rubin H. A biomolecular implementation of logically reversible computation with minimal energy dissipation. Biosystems. 1999 Oct; 52(1-3):15-23.
2. Shahabi S, Klein JP, Rinaudo PF. Primary psoas abscess complicating a normal vaginal delivery. Obstet Gynecol. 2002 May; 99(5 Pt 2):906-9.
3. Klein JP, Craner MJ, Cummins TR, Black JA, Waxman SG. Sodium channel expression in hypothalamic osmosensitive neurons in experimental diabetes. Neuroreport. 2002 Aug 7; 13(11):1481-4.
4. Craner MJ, Klein JP, Black JA, Waxman SG. Preferential expression of IGF-I in small DRG neurons and down-regulation following injury. Neuroreport. 2002 Sep 16; 13(13):1649-52.
5. Craner MJ, Klein JP, Renganathan M, Black JA, Waxman SG. Changes of sodium channel expression in experimental painful diabetic neuropathy. Ann Neurol. 2002 Dec; 52(6):786-92.
6. Klein JP, Jean-Baptiste M, Thompson JL, Bowers MB. A case report of hypomania following vagus nerve stimulation for refractory epilepsy. J Clin Psychiatry. 2003 Apr; 64(4):485.
7. Klein JP, Waxman SG. The brain in diabetes: molecular changes in neurons and their implications for end-organ damage. Lancet Neurol. 2003 Sep; 2(9):548-54.
8. Hains BC, Klein JP, Saab CY, Craner MJ, Black JA, Waxman SG. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. J Neurosci. 2003 Oct 1; 23(26):8881-92.
9. Klein JP, Tendi EA, Dib-Hajj SD, Fields RD, Waxman SG. Patterned electrical activity modulates sodium channel expression in sensory neurons. J Neurosci Res. 2003 Oct 15; 74(2):192-8.
10. Klein JP, Hains BC, Craner MJ, Black JA, Waxman SG. Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus. Neurobiol Dis. 2004 Mar; 15(2):221-8.
11. Klein JP, Khera DS, Nersesyan H, Kimchi EY, Waxman SG, Blumenfeld H. Dysregulation of sodium channel expression in cortical neurons in a rodent model of absence epilepsy. Brain Res. 2004 Mar 12; 1000(1-2):102-9.
12. Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. J Neurosci. 2004 May 19; 24(20):4832-9.
13. Klein JP, Kostina-O'Neil Y, Lesser RL. Neuro-ophthalmologic presentations of hemicrania continua. Am J Ophthalmol. 2006 Jan; 141(1):88-92.
14. Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, Bashyal C, Giblin K, Paul-Laughinghouse C, Wang F, Phadke A, Mission J, Agarwal RK, Englot DJ, Motelow J, Nersesyan H, Waxman SG, Levin AR. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia. 2008 Mar; 49(3):400-9.
15. Blumenfeld H, Lampert A, Klein JP, Mission J, Chen MC, Rivera M, Dib-Hajj S, Brennan AR, Hains BC, Waxman SG. Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis. Epilepsia. 2009 Jan; 50(1):44-55.
16. Klein JP, Cohen AB, Kimberly WT, Shah AS, Leiderman YI, Cestari DM, Dinkin MJ. Diffusion-weighted magnetic resonance imaging of bilateral simultaneous optic nerve infarctions. Arch Neurol. 2009 Jan; 66(1):132-3.
17. Krishnaswamy A, Klein JP, Kapadia SR. Clinical cerebrovascular anatomy. Catheter Cardiovasc Interv. 2009 Oct 9.
18. Klein JP, Ryther RC. Images in clinical medicine. Central nervous system hemorrhage. N Engl J Med. 2009 Oct 29; 361(18):1786.
 
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